Research Microscopy and Histology Core

The Research Microscopy and Histology Core provides a wide range of microscopy equipment and histological and microscopy services on a fee-for-service basis to researchers at Saint Louis University, as well as to researchers at other universities and businesses around the world.

The core is well equipped for all types of microscopy-related techniques and services.

Our technical staff will assist researchers in planning experiments, working at the microscopes and evaluating results. We also carry out microscopy projects for researchers at many different starting points. We are sensitive to the importance of getting results back to the researcher as quickly as possible and we endeavor to maintain the shortest turn-around-times consistent with sample volume and complexity.

Our Mission

  • Provide personalized, cost effective and quality sample preparation.
  • Provide excellent data collection, image processing and morphometric image analysis services.
  • Facilitate professional interpretation in imaging research projects.

Equipment and Services

Equipment

  • Olympus FV1000 laser scanning confocal microscope
  • Olympus FV1000 MPE laser scanning and multiphoton confocal microscope
  • JEOL 1200EX transmission electron microscope
  • JEOL 5800 scanning electron microscope
  • Olympus IX81 live cell imaging microscope
  • Arcturus Pixcell2 laser capture microscope
  • Olympus VS120 slide scanning system
  • Leica SP8 TCS STED 3X

Services

  • Fixation, processing, and sectioning of samples in paraffin, OCT and plastic
  • Routine and special histological stains
  • Immuno-histochemistry/immuno-fluorescence
  • Tissue microarrays
  • Whole slide scanning
  • Training
  • Research design

Please inquire about other services.  

Frequently Asked Questions 

Who utilizes your services?

Our clients come from within SLU as well as from other universities and private companies in the metropolitan St. Louis area and across the United States.

Where are you located?

We are located within the Saint Louis University School of Medicine in Schwitalla Hall, Room M102.  The entrance to the building has been relocated to 3545 Vista Avenue. Please enter at this address and a guard will direct you to our facility.

When is the lab open?
We are generally open Monday through Friday, from 9 a.m. to 5 p.m. but can make special arrangements to meet your needs. Check for special hours during the holiday seasons.
Can I submit clinical samples?    
In short, no. We only work with samples for research studies. Clinical samples can be submitted to either the Histopathology Lab (314-977-7874) or the Clinical Electron Microscopy Lab (314-977-7854). For research samples using human tissues, please check with us for policies regarding IRB approval. 
What do you charge?

Our prices are competitive with other facilities that offer microscopy services. Please contact us at nagelba@slu.edu or 314-977-7862 for a price quote 

How do I submit a sample?

Investigators within SLU can bring the sample to our lab or call us and to arrange pick up from a lab. Those in the St. Louis metropolitan area can bring the sample to our lab or send it via FedEx or private courier.  Out-of-state clients usually send samples via FedEx or UPS. 

How fast will I get results?
We are very cognizant of the fact that you need results in a timely manner. If you submit a small number of samples (one to five), we can obtain results relatively quickly. Expedited requests incur an additional fee. 
How will I be billed?
We bill on a monthly basis. You will receive an invoice from the Department of Pathology with remittance information.
Can I do my own scope work?

If you have been trained to use the microscopes, you can do your own scope work. There will be a charge for scope time, but no additional charge for RMHC personnel. Training times are scheduled between 1 to 3 p.m. on Mondays. Please contact us well in advance to schedule an appointment.

 
I don’t know if I want my samples embedded in paraffin or plastic. Can you tell me which would be the best for my experiments?
We suggest that you discuss your project with us at the outset to determine which procedures will yield the specific information you need. We can provide the appropriate fixative and even assist with dissections to ensure the best possible outcome for your studies. 
I don’t have a lot of money but I need microscopy for a study I’m doing. Can you work with me?
It may be possible that after we process and section the tissue, you can do the experiment in your own lab. If you are trained on the microscope, you can do the actual scope work, which is a savings.
Why should I use the RMHC?
We are passionate about microscopy. We have the tools and we know how to use them. We bring your images to life.